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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EXOC1
All Species:
39.7
Human Site:
S667
Identified Species:
67.18
UniProt:
Q9NV70
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NV70
NP_001020095.1
894
101982
S667
E
V
K
I
S
K
K
S
K
V
G
I
L
P
F
Chimpanzee
Pan troglodytes
XP_001142521
886
101061
S659
E
V
K
I
S
K
K
S
K
V
G
I
L
P
F
Rhesus Macaque
Macaca mulatta
XP_001087347
894
101935
S667
E
V
K
I
S
K
K
S
K
V
G
I
L
P
F
Dog
Lupus familis
XP_532380
894
102004
S667
E
V
K
I
S
K
K
S
K
V
G
I
L
P
F
Cat
Felis silvestris
Mouse
Mus musculus
Q8R3S6
894
101859
S667
E
V
K
I
S
K
K
S
K
V
G
I
L
P
F
Rat
Rattus norvegicus
NP_001019941
681
76652
G483
K
L
S
V
Q
S
S
G
S
R
R
S
Q
S
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506171
894
101975
S667
E
V
K
I
S
K
K
S
K
V
G
I
L
L
F
Chicken
Gallus gallus
XP_001232097
895
102211
S668
E
V
K
I
S
K
K
S
K
V
G
I
L
P
F
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_955891
892
101963
S665
E
V
K
I
S
K
K
S
K
V
G
I
L
P
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VVG4
889
102677
A665
K
L
H
K
R
S
K
A
I
L
P
Y
V
E
N
Honey Bee
Apis mellifera
XP_396967
859
98113
K633
T
K
V
N
R
R
N
K
C
G
I
L
P
Y
V
Nematode Worm
Caenorhab. elegans
Q20678
848
97279
T619
E
V
R
I
A
K
K
T
R
I
G
I
L
P
S
Sea Urchin
Strong. purpuratus
XP_787291
869
100242
S642
E
T
R
I
S
K
K
S
K
C
G
I
L
P
F
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SX85
887
100046
Q671
R
N
E
R
N
V
R
Q
M
G
V
L
P
Y
I
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.2
99.5
98.5
N.A.
97.1
70.9
N.A.
95
94
N.A.
84.6
N.A.
40.1
42
34.3
49.1
Protein Similarity:
100
98.2
100
98.8
N.A.
98.6
73.8
N.A.
97.1
96.6
N.A.
91.6
N.A.
62.4
62.5
54.5
68.7
P-Site Identity:
100
100
100
100
N.A.
100
0
N.A.
93.3
100
N.A.
100
N.A.
6.6
0
60
80
P-Site Similarity:
100
100
100
100
N.A.
100
20
N.A.
93.3
100
N.A.
100
N.A.
40
13.3
93.3
86.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
25.1
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
45.6
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
8
0
0
8
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
8
8
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
72
0
8
0
0
0
0
0
0
0
0
0
0
8
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
65
% F
% Gly:
0
0
0
0
0
0
0
8
0
15
72
0
0
0
0
% G
% His:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
72
0
0
0
0
8
8
8
72
0
0
8
% I
% Lys:
15
8
58
8
0
72
79
8
65
0
0
0
0
0
0
% K
% Leu:
0
15
0
0
0
0
0
0
0
8
0
15
72
8
0
% L
% Met:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% M
% Asn:
0
8
0
8
8
0
8
0
0
0
0
0
0
0
8
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
8
0
15
65
0
% P
% Gln:
0
0
0
0
8
0
0
8
0
0
0
0
8
0
0
% Q
% Arg:
8
0
15
8
15
8
8
0
8
8
8
0
0
0
0
% R
% Ser:
0
0
8
0
65
15
8
65
8
0
0
8
0
8
15
% S
% Thr:
8
8
0
0
0
0
0
8
0
0
0
0
0
0
0
% T
% Val:
0
65
8
8
0
8
0
0
0
58
8
0
8
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
8
0
15
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _